0000017487 00000 n 0000004765 00000 n 0 While their effectiveness varies from year to year, most provide modest to high protection against influenza. VAXIGRIP may be used during breast-feeding. <<87408FA5D6DFC94CB11D3CF1ACDD1B03>]/Prev 35154>> 0000000956 00000 n 0000005763 00000 n 0000001486 00000 n fd�}S��� K�7 ���� շ�ã]eh�.�����y�=�ާ�^��ΥIH,b{xDbj^,�T�^O'n�̷��B�(B�[~Z�7q��˨X]x�,� 0000009631 00000 n 0000004438 00000 n 0000005064 00000 n New versions of the vaccines are developed twice a year, as the influenza virus rapidly changes. 0000008342 00000 n 0000017274 00000 n 0000001666 00000 n Sanofi has a full-fledged vaccine portfolio, including quadrivalent as well as trivalent vaccines. 0000005288 00000 n 0000001362 00000 n

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Sanofi said on Tuesday that it's picking up Connecticut-based flu vaccine maker Protein Sciences in a deal worth $650 million up front and another $100 million in potential follow-up payments. 0000009210 00000 n Influenza vaccines, also known as flu shots or flu jabs, are vaccines that protect against infection by influenza viruses. 0000004515 00000 n 0000013207 00000 n ��a

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The company focuses on delivering effective vaccines by constantly upgrading its technologies used in manufacturing influenza vaccines.

Trivalents contain two flu A strains and one flu B strain and are available only as high-dose vaccines.

*Will be available in fall 2020, in time for the 2020-2021 flu season. 7�f T�?�p�� -��B8�b���4'�(Utޥ�u ���)��nOw���,��a�G&�!C����G,�ƝB#͚A�������Gӄ��� >R[s6�9v�(�nU9fԊ>1���U��N��, 0000005519 00000 n 0000002842 00000 n trailer 0000009872 00000 n 0000001820 00000 n 0000000016 00000 n startxref Sanofi also expects to benefit from “some price increases ,” in part because it is switching from the trivalent to quadrivalent forms of its Fluzone High-Dose vaccine.

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0000006673 00000 n 0000003728 00000 n endstream endobj 16 0 obj <�)/P -1324/R 3/U(.`p��207�#v�� )/V 2>> endobj 17 0 obj <>>> endobj 18 0 obj <> endobj 19 0 obj <>/Font<>/ProcSet[/PDF/Text]>> endobj 20 0 obj <> endobj 21 0 obj <> endobj 22 0 obj <> endobj 23 0 obj <> endobj 24 0 obj <> endobj 25 0 obj <> endobj 26 0 obj <> endobj 27 0 obj <> endobj 28 0 obj <>stream 0000013120 00000 n Flu vaccines can be used in all stages of pregnancy. PARIS - November 4, 2019 – The U.S. Food and Drug Administration (FDA) has approved a supplemental Biologics License Application for Fluzone ® High-Dose Quadrivalent (Influenza Vaccine) for use in adults 65 years of age and older. Other companies such as CSL Limited, GlaxoSmithKline plc, AstraZeneca, among others, have their effective products marketed globally. 0000012447 00000 n 0000011583 00000 n 0000010733 00000 n 0000003351 00000 n e�,���z�=.

47 0 obj <>stream 0000007453 00000 n 0000002384 00000 n (��]y��?�W�@��&�D%zb?�E.a~���at^y[�,(|�����H�� 0000002253 00000 n 15 33 Larger datasets on safety are available for the second and third trimester, compared with the first trimester; however, data from worldwide use of inactivated influenza vaccines do not indicate any adverse fetal and maternal outcomes attributable to the vaccine. Sanofi and GSK, which are partnered on a COVID-19 vaccine, are independently looking to the rising demand for flu shots to offset headwinds at other parts of their vaccine businesses.