K. Rajaguru, R. Suresh, A. Mariappan, S. Muthusubramanian, N. Bhuvanesh, … The reaction occurs with,Imidazole is incorporated into many important biological compounds.

How to use imidazole in a sentence.

An adaptation of the Debus method, it is called the,Imidazole can also be formed in a vapor-phase reaction. The name "imidazole" was coined in 1887 by the German chemist,Imidazole is a planar 5-membered ring.

It exists in two equivalent,Imidazole was first reported in 1858 by the German chemist,Imidazole can be synthesized by numerous methods besides the,The (1,5) or (3,4) bond can be formed by the reaction of an,The (1,2) and (2,3) bonds can be formed by treating a 1,2-diamino,The (1,2) and (3,4) bonds can also be formed from,This method proceeds in good yields for substituted imidazoles. 202,203 Pilocarpine, the only naturally occurring imidazole alkaloid, is used in clinical medicines for the treatment of glaucoma. All Rights Reserved. The most pervasive is the,One of the applications of imidazole is in the purification of,Imidazole has become an important part of many pharmaceuticals.


Azole antifungals are a group of medicines that contain an azole ring and inhibit the growth of a wide range of fungi. So far, we have obtained successful results using highly specific ligands with dissociation constants (,The acyl imidazole group of LDAI reagents acts as a moderately reactive electrophile. They do not represent the opinions of YourDictionary.com.Copyright © 2020 LoveToKnow. Imidazole can be formed via initial oxidation of the alkylamine to the corresponding imine, followed by attack of the amino group of the 3-alkylamino-6,8-dimethylpyrimido[4,5-c]pyridazine-5,7(6H,8H)-diones on this in situ formed imine.In addition to the ambient pH changing the alpha number of imidazole at any specific temperature, changes in temperature per se change not only the ambient pH but the pKa of the imidazole buffer system (see previous discussion).

Synthetic imidazoles are present in many,A number of substituted imidazoles, including,The substituted imidazole derivatives are valuable in treatment of many systemic,For comparison, another group of azoles is the triazoles, which includes,Some imidazole derivatives show effects on insects, for example,Imidazole itself has few direct applications. Employing low-affinity ligands would likely cause nonspecific labeling due to the presence of high concentrations of unbound LDAI reagents.

It was demonstrated that positioning this group on the protein surface close to the ligand-binding site facilitates acyl substitution reaction with nucleophilic amino acid residues (Lys, Ser, Thr, or Tyr) (,For chemical labeling of surface-exposed membrane proteins such as GABA,The 1,3-dipolar cycloaddition reaction of benzonitrile oxide to the imine function of a benzothiazepine yielded the fused 1,2,4-oxadiazoline,An interesting ring-expansion reaction of the tetracyclic oxazepine derivative,The many specific reactions of histamine are determined by the type of receptor (H,We use cookies to help provide and enhance our service and tailor content and ads. So in this case my protein samples after SEC would obviously have less Imidazole.

Pyrrol yields an analogous series: pyrazole,Like water and the amide bond in peptides, the,Canesten is best avoided in future and it is possible that other.Since metals like zinc, copper cobalt have a tendency to bind to non-specific sites,Elution buffer: 50 mm HEPES pH 7.5, 500 mM NaCl, 50 to 250 mM.The word usage examples above have been gathered from various sources to reflect current and historial usage. Imidazole is an organic compound with the formula C 3 N 2 H 4.It is a white or colourless solid that is soluble in water, producing a mildly alkaline solution. Example sentences with the word imidazole. The simplest member of the imidazole family is imidazole itself, a … It is aromatic, that is, readily undergoes halogenation, nitration, and sulfonation. They are found in various Pilocarpus species (Rutaceae) and fungi, e.g., ergothioneine and hercynine. A number of imidazole alkaloids found in marine sponges have been reviewed. imidazole example sentences. Imidazole is readily soluble i n water and alcohol and moderately soluble in ether. Imidazole, any of a class of organic compounds of the heterocyclic series characterized by a ring structure composed of three carbon atoms and two nitrogen atoms at nonadjacent positions. A ligand highly selective for the target protein should be chosen. 25 Method: the 4-methyl imidazole was separated from caramel by organic solvent, and be coloured, then be identified by HPLC.

In chemistry, it is an aromatic heterocycle, classified as a diazole, and has non-adjacent nitrogen atoms..

Imidazole alkaloids contain an imidazole nucleus and are derived from histidine. It is instead a precursor to a variety of agrichemicals, including,Salts of imidazole where the imidazole ring is the,Imidazole has low acute toxicity as indicated by the,InChI=1S/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5),InChI=1/C3H4N2/c1-2-5-3-4-1/h1-3H,(H,4,5),Except where otherwise noted, data are given for materials in their,CS1 maint: multiple names: authors list (,immobilised metal affinity chromatography,"Ueber Verbindungen des Thiazols (Pyridins der Thiophenreihe)","Ueber die Einwirkung des Ammoniaks auf Glyoxal","Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase","Effect of anti-fungal imidazoles on mRNA levels and enzyme activity of inducible nitric oxide synthase","Chapter 39: Antifungal and Antiviral Drugs",Ullmann's Encyclopedia of Industrial Chemistry,https://en.wikipedia.org/w/index.php?title=Imidazole&oldid=974170625,Pages using collapsible list with both background and text-align in titlestyle,Articles containing unverified chemical infoboxes,Creative Commons Attribution-ShareAlike License,89 to 91 °C (192 to 196 °F; 362 to 364 K),This page was last edited on 21 August 2020, at 13:08.