Ichthyosis vulgaris. It is due to mutation of certain genes and is usually an autosomal recessive, congenital ichthyosis (scaly skin condition). Report of a Case  It has the highest prevalence in the Caucasian population, especially in individuals with Norwegian ancestry. Terms of Use| sign up for alerts, and more, to access your subscriptions, sign up for alerts, and more, to download free article PDFs, sign up for alerts, customize your interests, and more, to make a comment, download free article PDFs, sign up for alerts and more, Archives of Neurology & Psychiatry (1919-1959), Subscribe to the JAMA Dermatology journal, FDA Approval and Regulation of Pharmaceuticals, 1983-2018, Global Burden of Skin Diseases, 1990-2017, Health Care Spending in the US and Other High-Income Countries, Life Expectancy and Mortality Rates in the United States, 1959-2017, Medical Marketing in the United States, 1997-2016, Practices to Foster Physician Presence and Connection With Patients in the Clinical Encounter, US Burden of Cardiovascular Disease, 1990-2016, Waste in the US Health Care System: Estimated Costs and Potential for Savings, Register for email alerts with links to free full-text articles. Home

With LI, the outer layer of skin called the epidermis is not normal and cannot protect the body like the healthy epidermis can. The aim is to keep the skin soft and attempt to reduce scaling. All Rights Reserved. There was no family history of ichthyosis or dry skin.

Page last reviewed: 15 July 2019 Next review due: 15 July 2022 Support links. There was no family history of ichthyosis or dry skin. At the age of 14, the patient recalled having similar lesions of short duration on the upper thighs. Last reviewed by a Cleveland Clinic medical professional on 03/01/2019. [Sponsored content]. 9500 Euclid Avenue, Cleveland, Ohio 44195 |. Ichthyosis isn't life-threatening, but it can be life-changing. If you have any concerns with your skin or its treatment, see a dermatologist for advice. If you have inherited ichthyosis, you'll have it for life.

Once it sheds, the baby develops scales over the entire body, including the soles and palms.

© 2020 American Medical Association. Accessed 3/5/2019. National Organization for Rare Disorders. The skin forms large, diamond-shaped plates that are separated by deep cracks. » There was no noticeable ectropion.

Foundation for Ichthyosis and Related Skin Types, Inc. National Center for Advancing Translational Sciences/Genetic and Rare Diseases Information Center (GARD). Your dermatologist can recommend treatments to help your skin look and feel better. 1973;108(2):275–276. The two most common underlying diseases are: As the collodion membrane dries up it can crack leading to fissures.

Note that this may not provide an exact translation in all languages, breadcrumbs The palms showed a mild thickening of the epidermis. Lamellar ichthyosis (LI) is a rare skin condition. Collodion baby. No recent medications were taken.Physical examination showed a healthy young man with prominent loose scales over most of the body with sparing of his face (Fig 1). At the age of 14, the patient recalled having similar lesions of short duration on the upper thighs. Ichthyosis Vulgaris: A Patient's Perspective. All Rights Reserved. National Organization for Rare Disorders. At the age of 14, the patient recalled having similar lesions of short duration on the upper thighs.

A paternal uncle may have had mild psoriasis.

Other supportive treatments such as intravenous fluid and tube feeding are often necessary. Accessed 3/5/2019. By continuing to use our site, or clicking "Continue," you are agreeing to our, 2020 American Medical Association.

Harlequin-type ichthyosis is a genetic disorder that results in thickened skin over nearly the entire body at birth. The newborn is born encased in a collodion membrane that sheds within 10-14 days.

For the most part, people who have ichthyosis vulgaris live a normal life, although they will probably always have to treat their skin. The collodion membrane is due to abnormal desquamation. All Rights Reserved, 1973;108(2):275-276. doi:10.1001/archderm.1973.01620230067028. We do not endorse non-Cleveland Clinic products or services. Sponsored content: melanomas are notoriously difficult to discover and diagnose. The disease rarely affects overall health. [ncbi.nlm.nih.gov] Prognosis Prognosis is variable. However, 10% of collodion babies have normal underlying skin – a mild presentation known as ‘self-healing’ collodion baby. Accessed 3/5/2019. Restricted movement of the chest can lead to breathing difficulties. Lamellar Ichthyosis and Psoriasis. Acquired ichthyosis may get better if the underlying cause is identified and treated. A moisturizer will help in the removal of scales and act as a barrier. Those who inherit two defective genes have a more severe form of ichthyosis vulgaris. The condition usually improves with age. Patients with this syndrome are usually born with a collodion membrane (a shiny, tight layer of skin over the body which is shed […] Congenital ichthyoses as a cause of collodion baby, OMIM – Online Mendelian Inheritance in Man, Foundation for Ichthyosis and Related Skin Types.

He also had the newly acquired scattered papulosquamous plaques on the trunk, hips, elbows, Milstein HG. Physical examination showed a healthy young man with prominent loose scales over most of the body with sparing of his face (Fig 1).
With your help, we can update and expand the website. Lamellar ichthyosis, type 1 is an autosomal recessive disorder caused by pathogenic variants in the TGM1 gene. Accessibility Statement. Other specialists that may need to be involved include: The life expectancy and difficulties that the collodion baby faces depend upon the particular underlying condition.





Children with the inherited form of the disorder usually have normal skin at birth, but develop scaling and roughness during the first few years of life.